Prevagen vs Ginkgo Biloba: There’s a Clear Winner

prevagen vs ginkgo biloba

Which is better, Prevagen or Ginkgo Biloba? We analyze these two brain supplements face to face in order to see which one will work better for you. 

[PREVAGEN VS GINKGO BILOBA SUMMARY]: For those of you that don’t want to read through the whole post, we’ve found Ginkgo Biloba to be a more effective and more affordable option. While you shouldn’t expect miracles from Ginkgo alone, it’s proven to help with brain circulation. Prevagen, on the other hand, only has two ingredients – one is vitamin D and the other is Apoaequorin, a jellyfish protein that isn’t proven to do anything.

-Click to See the Current Top Rated Brain Health Supplements-

>Top 3 Nootropic Stacks<

Prevagen vs Ginkgo Biloba – The Basics

Prevagen is all the rage in the nootropic world these days; this brain health supplement consists of only 2 ingredients, and it promises to help you with memory and cognitive function.

Ginkgo Biloba, on the other hand, is one of the oldest trees on Earth, and many people associate it with brain health. Ginkgo Biloba’s leaves been used for medicinal purposes for over 2,000 years. The leaves have historically been linked with memory benefits – especially in the elderly.

However, we’re here to tell you that Ginkgo isn’t just for older people. It’s a very underrated brain health ingredient among the youth, who might benefit from its nootropic activities just as much as old-school users.

So, Prevagen vs Ginkgo Biloba… which one takes the win? And can they compete with the current market leaders? Let’s dig deeper to find out!


Made by Quincy Bioscience, Prevagen is a popular brain supplement that claims to help with memory loss linked to aging. It’s marketed as the number one selling memory support product in stores.

But can it live up to the hype?

Well, we’re not so sure about that! There are a number of things about Prevagen that we feel are unfair. For one, the company that makes Prevagen has been sued by The Federal Trade Commission for false advertising claims and deception of its users.

Prevagen’s makers didn’t seem to care much, as they continue to run the same advertisements to this day. Their commercials include jellyfish graphics, where Prevagen’s active ingredient, is sourced from.

Another issue with Prevagen that it only has two ingredients, one of which probably doesn’t work. More on that in the next section.

Ginkgo Biloba

Ginkgo Biloba is one of the better known nootropics for improving cognition, memory, and mental clarity that are mildly impaired by aging or other factors.

[alert type=”info” icon-size=”normal”]For reference, the term ‘nootropic’ refers to a class of dietary supplements that have evidence that shows they can improve brain function.[/alert]

As for Ginkgo Biloba, it was one of the most famous memory pills back in the day. It was particularly popular amongst people age 55 and beyond to keep their brain function sharp. But over time, Ginkgo’s popularity faded away, overtaken by fancier stacks and commercially hyped nootropics.

The 3 Best Brain Health Supplements

We’ve picked the top three nootropic stacks that are available to you right now for cognitive support.


Prevagen vs Ginkgo Biloba Benefits

Prevagen’s manufacturers say that this product helps with mild memory loss linked to aging. Other potential benefits include:

  • Sharper mental function
  • Clearer thinking
  • Healthy cognition

As for Ginkgo Biloba, its benefits mostly revolve around mental clarity and reducing brain fog. It can also help in cases of:

  • Mild cognitive impairment
  • Memory decline

How They Work


Prevagen only contains 2 ingredients – vitamin D and Apoaequorin. Vitamin D is a great choice; this nutrient is needed for countless functions in your body. Including, testosterone production, mood and mental health.

However, unless you’re severely deficient in it, vitamin D alone won’t have much of an impact on your cognitive function.

As for the other ingredient, Apoaqeuorin, it’s sourced from a glowing jellyfish found in seas around North America. If you look it up online, you’ll see loads of marketing claims on Apoaequorin. This ingredient is supposed to help with memory, focus, and cognitive function. 

But what’s the real truth? Well, it doesn’t look nearly as nice as the marketing claims! The evidence behind Apoaqeuorin is very weak. One company-funded study showed some positive results, but the rest of the research looks disappointing. (2)

The problem with this ingredient is that it gets destroyed in your gut before even reaching your brain. Couple that with the lack of clinical evidence, and it’s clear that Apoaqeuorin is one big letdown.

On the whole, Prevagen’s formula isn’t impressive at all. Other than vitamin D, it has nothing that would want us to recommend this product to anyone. There are much better options available at the moment.


Ginkgo Biloba can help improve vasodilation, relaxing your blood vessels to boost brain circulation. Ginkgo’s active compounds might also help against blood clotting, making your blood more slippery and free-flowing.

The antioxidants in Ginkgo Biloba are also suggested to protect brain cells from oxidative stress, although, not much evidence is there to confirm all of these rumored benefits of Ginkgo.

Surprisingly, despite being used for thousands of years, Ginkgo is still a relatively underresearched compound. The current evidence is somewhat conflicted; some suggests that Ginkgo might benefit memory and blood flow to the brain, while other evidence says it only works in older people – and the effects themselves aren’t that impressive. (1)

A single-ingredient nootropic like Ginkgo is good, but it can’t provide the same level of cognitive support as proven nootropic stacks with multiple ingredients.

Side Effects

Although Prevagen’s makers insist their product doesn’t cause any side effects, some users did report headaches, anxiety, difficulty sleeping, dizziness, and nausea. According to WebMD, the main ingredient in Prevagen is “possibly safe” to use for up to 90 days. However, WebMD also states: “No high-quality research has evaluated side effects caused by apoaequorin.”

As for Ginkgo Biloba, it’s considered safe for most people when taken in the right doses. In some rare cases it might cause stomach upset, allergic skin reaction, and headaches. If you do experience any side effects from any supplement, discontinue use and call your doctor.


For a product with only two ingredients, Prevagen is a little expensive. Depending on where you buy it, the cost can get as high as $59.95 plus shipping for one month supply.

Ginkgo Biloba’s price teeters even more. The cost depends on multiple factors, such as the quality of the Ginkgo extract, the number of capsules, and the brand. Always make sure to buy from reputable sources!

Anything Else to Consider?

Just keep in mind that a supplement isn’t going to solve all of your goals. You should always ensure that you’re eating a good diet and staying active before thinking about taking a supplement to support your cognitive health.

Only when you’ve got your bases covered, you might want to supplement with a high quality, professional brain health supplement that addresses multiple aspects of mental performance.

-See This Year’s Top Rated Brain Health Supplements-

>Top 3 Nootropic Stacks<

Conclusion on Prevagen vs Ginkgo Biloba

So, which one is the better option? Ginkgo Biloba or Prevagen? If you’ve been with us throughout this review, it’s pretty clear that the answer here is Ginkgo Biloba.

It’s got more evidence backing it up, whereas Prevagen only has two ingredients, one of which is vitamin D, and the other ingredient doesn’t work.

So, while Ginkgo takes the win here, we don’t currently rate it as one of the very best nootropic supplements available right now. It’s good for circulation, but then again, so are many other nootropics. And it’s better to stack more than just one ingredient if you want complete brain optimization.

The 3 Best Brain Health Supplements

We’ve picked the top three nootropic stacks that are available to you right now for cognitive support.



  1. Ginkgo Biloba. (source)
  2. Apoaequorin. (source)

More Reviews

About Valentino M. 93 Articles
Valentino is a nutritionist, author, spiritual practitioner, and health coach. He's been researching nutrition and brain health since 2015, and has launched Valentino's Naturals to help people maximize their cognitive performance. When he isn't writing, Valentino loves to travel around Europe, spend time recharging in nature, and research topics within his field of expertise. More...


  1. Hi I’ve been on Gingo Biloba for about 13 years following an Anoxic Brain Injury September 2007 while runny my final 1/2 Marathon. I was without oxygen for 17 minutes so I was told. I’ve heard of other’s out now. Since Gingo Biloba is over the counter, I’m checking with my Neurologist’s to for opinions?

    • Hi Tym,

      It’s best to check with your neurologist and your MD on this. We don’t give any medical advice at Valentino’s Naturals!

Leave a Reply

Your email address will not be published.